Precision Blood Pressure Management.

A complete hemodynamic profile in under 5 minutes, allowing clinicians to treat the cause, not just the number.

The Opportunity

Blood pressure alone doesn't explain the cause.

Without a hemodynamic profile, it is incredibly difficult to tell whether high BP is driven by vasoconstriction, a hyperdynamic circulation, or a mixed profile.

The Missing Piece

Adding functional hemodynamics to routine vital signs gives you a more complete picture, leading to more confident and personalized prescribing decisions.

Uncovering Hidden Risk

Underlying hyperdynamic circulation or extreme vasoconstriction can mask severe cardiovascular risk even when numbers appear somewhat normal. NICaS reveals this physiology.

NICaS Software DashboardNICaS Live Signals

The Solution

Functional Cardiovascular Intelligence.

In minutes, NICaS turns a single non-invasive test into a complete hemodynamic profile, delivering the same class of data once available only through invasive catheterization in acute hospital care.

Physicians see whether high blood pressure is driven by volume, vascular resistance, or cardiac output, and match therapy to the actual cause.

NICaS Dashboard and Device

How it works

Regional Impedance Cardiography (RIC)

NICaS utilizes the principle that blood conducts electricity better than surrounding tissue. By passing a harmless, imperceptible current through two sensors on the wrist and contralateral ankle, it measures resistance changes with each heartbeat.

The device analyzes these minute signals via proprietary algorithms to derive cardiac output and fluid parameters, providing a complete hemodynamic profile.

The Reach of NICaS

One Overlooked Cause.
Seven Clinical Applications.

Hypertension is the shared physiological driver behind cardiac risk, kidney decline, stroke, and aging. NICaS provides clarity across disciplines.

1Hypertension

Identify the true driver of high blood pressure: is it driven by elevated cardiac output, high vascular resistance, or volume overload?

2Heart Failure

Support hemodynamic and volume-guided management. Tailor therapy to each patient's exact physiology rather than symptoms alone.

3Emergency Care

Rapid triage at the bedside in minutes. Differentiate cardiogenic shock from volume overload with no lines and no delay.

4Dialysis & Nephrology

Track physiology across dialysis sessions. Manage intradialytic hypotension and confidently guide dry-weight decisions.

5Preventive Cardiology

See risk before it becomes disease. Surface functional cardiovascular changes early and track them over time to optimize care.

6Executive Health

The dashboard your heart deserves. A complete non-invasive resting hemodynamic performance assessment in under 5 minutes.

7Home Monitoring

Hospital-grade hemodynamics at home. Remotely follow up and titrate medication for frail patients between clinic visits.

Same blood pressure, different patients.

Treat the underlying physiology, not just the symptom. Consider two patients, both presenting with an identical blood pressure:

Patient A

160/95 mmHg
High Cardiac Output
Strong Pump
More Flow
Normal Vessels

Treatment Focus: Reduce Cardiac Output

Patient B

160/95 mmHg
High Peripheral Resistance
Normal Pump
High Resistance
Constricted Vessels

Treatment Focus: Reduce Resistance

"Blood pressure measures pressure.
NICaS measures why."

From Initial Diagnosis to Longitudinal Tracking

Once therapy is matched to the patient's hemodynamic profile, NICaS measures trends across subsequent visits to confirm therapeutic response and fine-tune treatment.

1. MeasureEstablish baseline hemodynamics
2. TreatPrescribe targeted therapy
3. Track & OptimizeVerify & adjust across visits

The NICaS Advantage

Real, tangible advantages that transform cardiovascular care delivery.

100% Non-invasive

No catheters, no risk. Completely safe for any patient.

< 5 Minute Exam

Chair-side, immediate hemodynamic report in minutes.

Seamless Workflow

Patients stay fully clothed. The exam fits effortlessly into routine clinic visits.

Easy to Operate

Any trained professional (MA, RN, or technician) can run it with a short learning curve. No sonographer required.

Cloud-Ready & Remote

One professional can review multiple patients remotely.

Portable

Small, quiet, and easily usable in any care setting.

Reveals the Cause

Reveals why the patient is unstable (volume, peripheral resistance, perfusion), not just the symptom.

One device. Every setting.

NICaS fits into your workflow, not the other way around.

In the Clinic

A routine chair-side test that fits perfectly into standard clinic workflow without requiring any extra specialized staff or dedicated procedure rooms.

In Emergencies

Enables rapid triage of cardiogenic shock vs. volume overload, delivering an immediate and accurate perfusion picture when every minute counts.

In Home Care

Compact, highly portable, and remarkably comfortable for frail patients, allowing for remote follow-up and confident medication titration at home.

14,0581
Patients Studied

Based on a real-world observational cohort, not randomized-controlled-trial endpoints.

>90%2
Hypertension Control

Reported in independent studies and customer experience.

90%3
Readmission Decrease

In heart-failure patients reported by major hospital users.

<5
Minute Exam

Fast, operator-independent results with no undressing.

1 Sanidas, E. et al. (2026). American Journal of Medicine.2 Independent studies on hemodynamic-guided hypertension management.3 Hospital readmission data reported by clinical users.
Diagnostic Precision

Clinical Insights at a Glance

Seven core hemodynamic, vascular, and fluid parameters derived simultaneously in a single non-invasive test.

Proprietary MetricLeft Ventricular Contractility

Granov-Goor Index (GGI)

A signature non-invasive index for assessing left ventricular systolic performance and contractility. Validated in clinical trials with 89% sensitivity and 96% specificity for detecting LV dysfunction without echocardiography.

Flow & Volume

Stroke Volume & Index (SV/SVI)

Measures the exact volume of blood ejected per beat, providing immediate, actionable guidance on fluid responsiveness and inotropic titration.

Global Perfusion

Cardiac Output & Index (CO/CI)

The primary measure of global cardiac performance and systemic blood flow, ensuring organs receive adequate and sustained oxygen delivery.

Vascular Afterload

Total Peripheral Resistance (TPR)

Determines whether blood pressure changes are driven by arterial vasoconstriction or vasodilation, enabling targeted vasoactive prescribing.

Fluid Balance

Total Body Water (TBW)

Accurately quantifies fluid overload or intravascular depletion, providing essential volume guidance for heart failure and dialysis care.

Hydraulic Reserve

Cardiac Power Index (CPI)

Evaluates cardiac pumping performance using the Cardiac Power Index and functional reserve, a potent prognostic indicator in acute cardiovascular care.

Chronotropic Status

Heart Rate (HR)

Provides continuous baseline chronotropic assessment integrated seamlessly with flow, volume, and vascular resistance parameters.

The NICaS Ecosystem

More than a device, NICaS is a complete platform for managing cardiovascular health.

Knowledge Center

Clinical, training, and marketing resources, Q&A videos, and simulator access.

Dashboard

Cloud platform for managing multiple test results and devices from anywhere seamlessly.

Simulator

Real-world test scenarios to optimize training and ensure rapid operator certification.

Clinical Decision Support

Hemodynamic profiling and interpretation aids that help physicians match therapy to each patient's physiology. NICaS informs the decision — the clinician always makes the final call.

Measure Cardiovascular Performance Beyond Blood Pressure

Non-invasive hemodynamic assessment providing actionable cardiovascular insights for hypertension, heart failure, dialysis, emergency care, longevity and preventive medicine.

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Better Insight

See the functional cause

Better Decisions

Data-driven therapy

Better Control

Hit targets faster

Better Lives

Improved patient outcomes

Cleared or registered in 10+ countries worldwide