Clinical Solutions

One overlooked cause. Seven clinical applications.

Hypertension

Beyond the numbers.

The Evolution of Blood Pressure Management

1
MercuryManual auscultatory measurement
2
DigitalAutomated, convenient & consistent
3
24-hr ABPMCaptures daily variability & patterns
4
AI Risk ScoringPredicts event risk from data
Functional HemodynamicsReveals the physiology behind the number

NICaS guides you through distinct physiological treatment pathways, ensuring you treat the underlying cause of hypertension:

Patient A

High Cardiac Output

Hyperdynamic circulation. The heart is pumping too much volume, raising the pressure.

Target StrategyBeta-Blocker
Different Physiology. Different Treatment.
Patient B

High Peripheral Resistance

Vasoconstriction. Tight vessels are forcing the heart to work harder against high resistance.

Target StrategyVasodilator / CCB
Different Physiology. Different Treatment.
Patient C

Fluid Overload

Excess intravascular fluid volume driving up the pressure, independent of pump function.

Target StrategyDiuretic
Different Physiology. Different Treatment.

Traditional Clinic

BP
History
ECG
Empiric therapy
Interval review

What We Know

The symptom (high blood pressure). Basic electrical function (ECG). General risk factors.

What's Missing

The physiological driver. Is the pump working too hard, or are the vessels too tight?

Guided by the number alone

Truevitals NICaS Clinic

Blood Pressure
Cardiac Output & SVPump efficiency
ResistanceVessel tone
Fluid StatusVolume

= Physiology-Guided Decisions

Target the specific cause, confirm response immediately, and reach BP goals sooner.

Understand Physiology. Personalize Treatment.

92% BP Control

Reported by the second visit when therapy was guided by hemodynamics.
Based on a real-world observational cohort (American Journal of Medicine, 2026), not randomized-controlled-trial endpoints.

Heart Failure

Manage the physiology, not just the symptoms.

NICaS supports hemodynamic- and volume-guided heart failure management. By profiling cardiac output, vascular resistance, cardiac power, and total body water in a single non-invasive test and tracking the trend across visits, it helps clinicians tailor therapy to each patient's physiology rather than symptoms alone, and monitor response over time.

The Workflow

Patient
Assessment
NICaS
Exam
Interpretation
(CO, SV, TPR)
Targeted
Decision
Follow-up
(Verify Response)

NICaS fits into your workflow, not the other way around.

Cardiac OutputVascular ResistanceCardiac PowerTotal Body Water

Emergency & Critical Care

Rapid answers when minutes matter.

At the bedside, NICaS delivers a non-invasive hemodynamic picture in minutes, with no arterial line and no catheter. It helps clinicians distinguish a perfusion problem from volume overload and gauge cardiac power, a parameter shown in critical-care studies to be a strong prognostic indicator.

Rapid triage

Differentiate cardiogenic shock from volume overload with an immediate flow-and-perfusion read.

No lines, no delay

Fully non-invasive; no arterial or central line placement required.

Prognostic insight

Cardiac Power Index, a parameter associated with outcomes in critical illness.

Dialysis & Nephrology

Beyond Creatinine. Beyond eGFR. Beyond Dry Weight.

Hemodynamic profiling allows dialysis centers to track physiology across every session. Manage intradialytic hypotension and guide dry-weight decisions by confirming adequate cardiac reserve before and during treatment.

The Cardio-Renal Loop

Two organs, one closed system. Failure in one accelerates failure in the other.

Cardiac FunctionPump & Output
Blood PressureSystemic Resistance
Renal PerfusionKidney Function
Fluid BalanceVolume Status

The NICaS Advantage: Standard bioimpedance / body-composition monitors only measure fluid balance. NICaS measures fluid balance plus cardiac output, providing the complete loop to safely manage dry weight without causing intradialytic hypotension.

Same Weight. Different Physiology.

Two dialysis patients presenting at 75kg. Standard bioimpedance / body-composition monitors suggest both are at dry weight. NICaS reveals the true cardiovascular risk.

Patient A
75 kg

Compensated

Total Body WaterNormal
Cardiac PowerStrong (0.8 W)
Outcome: Safe for standard ultrafiltration. Heart can tolerate the fluid removal.
Patient B
75 kg

Vulnerable

Total Body WaterNormal
Cardiac PowerWeak (0.4 W)
Outcome: High risk of intradialytic hypotension (IDH). Heart lacks reserve to compensate for volume shifts. Requires careful titration.

Preventive Cardiology

See risk before it becomes disease.

Blood pressure and risk scores describe probability; NICaS measures how the cardiovascular system is actually performing today. By quantifying cardiac output, vascular resistance, and cardiac power, it can surface functional changes early and track them over time as patients are managed.

The Evolution of Cardiac Assessment

1
Physical ExamSymptoms & physical signs
2
ECGElectrical activity
3
EchoStructure & function
4
BiomarkersMolecular & anatomical data
Functional IntelligenceHow the heart & circulation truly perform

Executive Health

The dashboard your heart deserves.

From Reactive to Proactive Care

1
Symptom Management
2
Annual Physical
3
Risk Stratification
Continuous Optimization

NICaS adds a functional cardiovascular performance assessment to longevity and executive-health workups, delivering a non-invasive resting hemodynamic measurement completed in under 5 minutes.

It complements biological age, DEXA, coronary calcium scoring, MRI, and laboratory biomarkers by quantifying how the cardiovascular system is performing today, and by tracking that performance over time.

DEXA ScansBody Composition
BiomarkersBlood Panels
VO₂ MaxMetabolic Fitness
GeneticsPredisposition
HemodynamicsThe Missing Pillar
NICaS
Each Scored 0–100 • Automatic Interpretation (Excellent to Reduced)

The NICaS Cardiovascular Performance Report

Overall Cardiovascular Performance Score
Composite

A comprehensive composite of the patient's functional cardiovascular performance.

AUTOMATIC SCORING0–100 Scale • Plain-Language
Heart Performance Score
0–100

cardiac pumping performance.

Derived from stroke volume, stroke index, cardiac index, and cardiac power index.
Vascular Function Score
0–100

vascular resistance and arterial load.

Derived from total peripheral resistance index and mean arterial pressure.
Cardiac Power & Workload Score
0–100

myocardial workload and pumping power.

Derived from cardiac power index, cardiac index, heart rate, and TPRI.
Fluid Balance Score
0–100

hydration/volume status.

Derived from total body water.
Report Features & Capabilities
Hemodynamic Classification

Categorizes the patient's circulatory profile.

Automatic Clinical Interpretation

Plain-language explanation of each score.

Longitudinal Trend Analysis

Compares assessments over time to show response to lifestyle changes and interventions.

“Objective, repeatable monitoring of cardiovascular treatment response, in a simple patient-friendly report.”

Home Monitoring

Hospital-grade hemodynamics at home.

NICaS is portable, simple to operate, and comfortable for frail patients, and its cleared intended use includes home-healthcare programs. That enables remote follow-up and confident medication titration between clinic visits.

Portable & simple

Small and quiet; a trained professional can run it in any setting.

Remote follow-up

Review results from anywhere and titrate therapy between visits.

Comfortable

Non-invasive and quick, well suited to elderly or frail patients at home.